ENHANCED THERAPEUTIC EFFICACY OF DOXORUBICIN AGAINST MULTIDRUG-RESISTANT BREAST CANCER WITH REDUCED CARDIOTOXICITY

Enhanced therapeutic efficacy of doxorubicin against multidrug-resistant breast cancer with reduced cardiotoxicity

AbstractDoxorubicin (DOX), a commonly used anti-cancer drug, is limited by its cardiotoxicity and multidrug resistance (MDR) of tumor cells.Epigallocatechin gallate (EGCG), a natural antioxidant component, can effectively reduce the cardiotoxicity of DOX.Meanwhile, EGCG can inhibit the expression of P-glycoprotein (P-gp) and reverse the MDR of tumo

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Phage Endolysins as Potential Antimicrobials against Multidrug Resistant Vibrio alginolyticus and Vibrio parahaemolyticus: Current Status of Research and Challenges Ahead

Vibrio alginolyticus and V.parahaemolyticus, the causative agents of Vibriosis in marine vertebrates and invertebrates, are Patient Lifts also responsible for fatal illnesses such as gastroenteritis, septicemia, and necrotizing fasciitis in humans via the ingestion of contaminated seafood.Aquaculture farmers often rely on extensive prophylactic use

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